Unit Code: MLS600

Unit Name: Metabolic Biochemistry

Description: The purpose of this course is to provide students with knowledge in laboratory medicine in which chemical and biochemical methods are applied to the study of diseases. Clinical biochemistry I is the area of clinical pathology that is generally concerned with biochemical analysis of the bodily fluids. Biochemical tests comprise over one-third of all hospital laboratory investigations and thus this is one of the highly automated departments in clinical pathology. This syllabus encompasses the basic clinical biochemistry of proteins, enzymes, nutrition, cardiovascular disease, lipids and endocrinology. The first year of Clinical Biochemistry focuses more on the basic principles of metabolism and diagnostic technologies and prepares the students for MLS 707. Practical sessions for each topic is described in the practical manual, a companion to course descriptor.

Learning Target Outcomes: On successful completion of this course, students will be able to: 1. Apply knowledge obtained from basic biochemistry to biochemistry profile testing. 2. Explain the principles of optical techniques, colorimetry and turbidimetry. 3. Describe the significance and measurement of plasma proteins and enzymes of clinical significance. 4. Investigate glucose measurement and its implications in Diabetes Mellitus 5. Evaluate biochemical aspects and laboratory diagnosis of Myocardial Infarction. 6. Compare the clinical aspects of lipids, lipoproteins nutritional vitamins and minerals in a clinical biochemistry laboratory. 7. Discuss hormones in the body and mechanisms involved in the regulation of hormone secretion. 8. Design guidelines for laboratory quality control, information system and ethics in a clinical biochemistry laboratory.

Prerequisite: Pass in the BMLS Year 1

Prerequisite Sentence: N/A

Credit Point: 15

Offered In: Semester 1