Unit Code: MLS506

Unit Name: Molecular Biology & Genetics

Description: Molecular biology and Genetics overlaps with the disciplines of biology, chemistry, biochemistry, biotechnology, microbiology and bioinformatics. The unit is designed to enable students gain an understanding of the interaction between various systems of cells, including the interrelationship of DNA, RNA and protein synthesis and how these interactions are regulated. The students should have an understanding of how genetic information controls the structure, function and development of normal and abnormal cells, and eventually the organism as a whole. The knowledge acquired from this unit and the complementing units (biochemistry, haematology, immunology and microbiology) will introduce the student to the rapid development in the field of molecular diagnostic and molecular medicine. The practical aspect of the course aims to equip students with sufficient fundamental skills to apply them to a broad range of positions requiring these skills.

Learning Target Outcomes: On successful completion of this course, the students will be able to: • Discuss the knowledge of the fundamentals of Nucleic Acids, the process of DNA replication, protein synthesis and the theory of Central Dogma. • Demonstrate the knowledge of the components of cell cycle and Chromosomes. • Distinguish between the principles of genetics application and learn the various techniques used in Molecular Biology • . Discuss the patterns of inheritance • Demonstrate the knowledge of the fundamental processes of genetics in microorganisms. • Demonstrate the knowledge of mutations and determine the role of mutations in causing genetic disorders. • Discuss how mutation in single cell cycle checkpoint leads to cancer

Prerequisite: Minimum Entry Requirement

Prerequisite Sentence: N/A

Credit Point: 15

Offered In: Semester 2