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Unit Code: CLT504

Unit Name: Clinical Biochemistry

Description: The CLT 504 Clinical Biochemistry is a branch of laboratory medicine in which chemical and biochemical methods are applied to the study of diseases. Biochemistry has become the foundation of understanding biological processes in the medical field. It has provided insight into the causes of many diseases in humans at both biochemical and genetic level which than allows for ways to treat or cure these diseases. An understanding of pathophysiological basis of diseases is examined including: Proteins; Enzymes; Nutrition; Diabetes Mellitus and Hypoglycemia; Lipids and Cholesterol; Renal Function. This unit also examines on a range of chemical analyses on biological materials using established biochemical criteria to help in laboratory diagnosis. This unit is composed of, and it aims to bring together the physiology, biochemistry and relevant pathology for the proper use of the laboratory and enable interpretation of biochemistry results. Biochemical tests are examined including: Fluid and Electrolyte Balance; Arterial Blood Gas; Acid Base Balance; Amniotic Fluid and Neonatal Diseases; Liver Function; Practical aspects of Biochemistry analyzers will be examined with emphasis on clinical laboratory attachments.

Learning Target Outcomes: On successful completion of this course, the students will be able to : 1. Explain the importance, laboratory testing, quality control in the clinical biochemistry and ethical issues pertaining to biochemistry. 2. Discuss the principal plasma proteins and testing by use of electrophoresis and perform plasma protein testing. 3. Identify the enzymes of clinical significance and its importance and perform the testing of the enzymes. 4. Discuss biochemical aspects and laboratory diagnosis of myocardial infarction. 5. Discuss glucose homeostasis and its implications in Diabetes Mellitus. 6. Discuss the clinical aspects of lipids and lipoproteins and perfom the testing of lipids. 7. Discuss the biochemical aspects of renal and its function. 8. Discuss the biochemistry of hormones and the mechanisms involved in the regulation of hormone secretion. 9. Explain the biochemical regulation of fluid and electrolyte. 10. Discuss liver function and the biochemical tests done to test for diseases.

Prerequisite: Pass in Year 13 as per MER

Prerequisite Sentence: N/A

Credit Point: 15

Offered In: Semester 1