Unit Code: CHM926

Unit Name: Advanced Medicinal Chemistry

Description: This course applies principles learned in biochemistry and advanced organic chemistry courses towards the design and discovery of new medicines. Steps involved in the discovery of medicine will be discussed using case studies. The course will discuss how biochemical principles of choosing a drug target is determined based on receptor sites in enzyme, cell wall, a protein or DNA or by interrupting a metabolic cycle. Using chemical principles, how a lead compound is selected and developed into a marketable drug. Tools available for the drug discovery process - lead compound selection, how to optimize the effectiveness of a drug, and synthesis using chemical principles will be discussed. Finally, drug side effects, ethics, environmental effects, laws and legislation controlling the use of drugs will also be discussed.

Learning Target Outcomes:

Prerequisite: PGD/ M.Sc. Year 1 Pass or equivalent

Prerequisite Sentence: N/A

Credit Point: 30

Offered In: Semester 1,2