Unit Code: CHM802

Unit Name: Chemistry of Natural Products

Description: Natural product chemistry aims to provide overview of chemistry of secondary metabolites. It will also serve as an initial platform for more advanced excursion in to the origin of natural products and their potential roles in drugs discovery. Natural products have been a fertile area of chemical investigation for many years, driving the development of both anaiytical chemistry and of new synthetic reactions and methodologies. The course builds upon fundamental chemical principles and guides the students through a wealth of diverse secondary metabolities with particular emphasis on those used in medicine. The chemistry and biological activity of the following classes of natural products viz steroids, terpenoids, saponins, alkaloids, prostagladins, polyacetylenes, quinones, pheromones, oxygen heterocyclic compounds will be discussed.

Learning Target Outcomes: On successful completion of this course, students will be able to : a) Explain the process and difference between synthetic and natural product biosynthesis pathways. b) Understand different biosynthesis pathways. c) Identify the natural resources for potential medicinal, agrochemical and industrial applications. d) Classify natural products based on structure and functions and applications. e) Use various extractions, chromatographic and spectroscopic techniques to isolate, detect and characterize compounds from natural sources. f) Explain the mode of action, metabolism, resistivity and selectivity of any group of compounds (pharmaceuticals and pesticides). g) Determine the synthetic pathway of medicinal compounds through natural product precursors. h) Summarize and present the work in a related area before colleagues with the same or higher level of knowledge.

Prerequisite: Bachelor Degree with Chemistry as a major subject

Prerequisite Sentence: Bachelor Degree with Chemistry as a major subject

Credit Point: 20

Offered In: Semester 1,2