Unit Code: CHM807

Unit Name: Bio-Inorganic Chemistry

Description: This course help student unify inorganic chemistry concepts with chemistry of metal ions in biology. Building from basic inorganic and coordination chemistry\'s mechanistic, structural and spectroscopic issues course would introduce to multiple roles of metal ions in biological systems. Specific areas to be covered include coordination chemistry, inorganic chemistry of biologgical systems. Pathways of metal assimilation, storage and transport, as well as metal homeostasis, roles of sodium and potassium, magnesium, calcium, zinc; specific classes of system in detail iron, copper, nickel and cobalt, manganese, molybdenum containing biological compounds be discussed. Role of inorganic pharmaceutical compounds in treatment and diagnostic would be discussed in details.

Learning Target Outcomes: On successful completion of this course, students will be able to : a) Correlate the chemistry of metal ions with their roles in living systems b) Explain the intricacies of metal ion transport and storage c) Explain the roles of alkali metal ions in potential regulation and their importance in antimicrobial treatments. d) Explain the roles of Mg in phosphate and nucleic acid stabilization. e) Explain the roles of Ca in structure and cellular communications. f) Appreciate the importance of metal coordination hydrolase functions. g) Appreciate redox and electron transfer functions of metalloenzymes h) Appreciate the significance of model compounds in understanding biological roles. i) Appreciate the importance of metal compounds in treatment and medical diagnosis.

Prerequisite: CHM701, CHM707

Prerequisite Sentence: or work experience in a related area

Credit Point: 20

Offered In: Semester 1,2